CD3G Recombinant Protein
Source : E.coli. CD3G Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 117 amino acids (23-116a.a.) and having a molecular mass of 13.1kDa. CD3G is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. CD3-gamma polypeptide is encoded by CD3 Gamma (CD3G) which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, configures the T-cell receptor-CD3 complex. The T-cell receptor-CD3 complex takes part in coupling antigen recognition to numerous intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Deficiencies in this gene are associated with T cell immunodeficiency.
Product Specifications
Product Name Alternative
T-cell surface glycoprotein CD3 gamma chain||CD3-GAMMA||T3G||CD3G.
Purification
Greater than 90% as determined by SDS-PAGE.
Components
CD3G protein solution (1mg/mL) containing 20mM Tris-HCl buffer (pH 8.0), 0.4M urea and 10% glycerol.
Storage Conditions
Frequently Asked Questions
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