CD244 Recombinant Protein

Source : E.coli. CD244 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 230 amino acids (19-224 a.a) and having a molecular mass of 25.5kDa.CD244 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Cluster of Differentiation 244 (CD244/Natural Killer Cell Receptor 2B4) contains 2 Ig-like (immunoglobulin-like) domains. CD244 is a cell surface receptor expressed on natural killer (NK) cells (and some T cells) which mediate non-major histocompatibility complex (MHC) restricted killing. NK-cell and target cells interaction via the CD244 receptor is believed to modulate NK-cell cytolytic activity. CD244 molecules function in eosinophil adhesion and chemotaxis, and have a role in the pathophysiology of allergic rhinitis (AR) .

Product Specifications

Product Name Alternative

Natural killer cell receptor 2B4||NK cell activation-inducing ligand||NAIL||NK cell type I receptor protein 2B4||NKR2B4||h2B4||CD244||2B4||Nmrk||SLAMF4.

Purification

Greater than 85% as determined by SDS-PAGE.

Components

CD244 protein solution (0.5mg/mL) containing 20mM Tris-HCl buffer, pH8.0 and 0.4M Urea.

Storage Conditions

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) .Avoid multiple freeze-thaw cycles.

Amino Acids

MGSSHHHHHH SSGLVPRGSH MGSHGKGCQG SADHVVSISG VPLQLQPNSI QTKVDSIAWK KLLPSQNGFH HILKWENGSL PSNTSNDRFS FIVKNLSLLI KAAQQQDSGL YCLEVTSISG KVQTATFQVF VFDKVEKPRL QGQGKILDRG RCQVALSCLV SRDGNVSYAW YRGSKLIQTA GNLTYLDEEV DINGTHTYTC NVSNPVSWES HTLNLTQDCQ NAHQEFRFWP.