CD2 GST Recombinant Protein

Source : Escherichia Coli. CD2 Human Recombinant (aa 25-209) expressed in E.coli, shows a 46 kDa band on SDS-PAGE.The CD2 is purified by proprietary chromatographic techniques. CD2 which is also known as E-rosette receptor, T11 and lymphocytefunction antigen-2 (LFA-2) is expressed on T cells, thymocytes, and subset of natural killer cells. Human CD2 functions as the receptor for sheep erythrocytes, human CD58 (LFA-3), and CD15s (Sialyl Lewis X) . p56lck, p59fyn, CD3eta and CD3epsilon are tyrosine-phosphorylated after CD2 stimulation. CD2 plays a role in T cell activation, T- or NK-cell-mediated cytolysis, apoptosis in activated peripheral T cells, and regulation of T cell anergy.