C16ORF53 Recombinant Protein

Source : Escherichia Coli. C16ORF53 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 274 amino acids (1-254 a.a.) and having a molecular mass of 29.9kDa (Molecular weight on SDS-PAGE will appear higher) .C16ORF53 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. C16ORF53 is a component of a Set1-like multiprotein histone methyltransferase complex. C16ORF53 interacts with PAXIP1/PTIP; this interaction is direct and is necessary for the association with the rest of the PTIP complex. The C16ORF53 protein has a crucial role in maintaining genome stability, condensation of chromatin and progression through mitosis.

Product Specifications

Product Name Alternative

PAXIP1-associated protein 1||PTIP-associated protein 1||PA1||C16orf53||GAS.

Purification

Greater than 85.0% as determined by SDS-PAGE.

Components

C16ORF53 protein solution (1mg/mL) containing 20mM Tris-HCl buffer (pH 8.0), 10% glycerol, 2mM DTT and 0.1M NaCl.

Storage Conditions

C16ORF53 Human Recombinant although stable at 4°C for 1 week, should be stored below -18°C. Please revent freeze thaw cycles.

Amino Acids

MGSSHHHHHH SSGLVPRGSH MSLARGHGDT AASTAAPLSE EGEVTSGLQA LAVEDTGGPS ASAGKAEDEG EGGREETERE GSGGEEAQGE VPSAGGEEPA EEDSEDWCVP CSDEEVELPA DGQPWMPPPS EIQRLYELLA AHGTLELQAE ILPRRPPTPE AQSEEERSDE EPEAKEEEEE KPHMPTEFDF DDEPVTPKDS LIDRRRTPGS SARSQKREAR LDKVLSDMKR HKKLEEQILR TGRDLFSLDS EDPSPASPPL RSSGSSLFPR QRKY.