BSND Recombinant Protein
Source : Escherichia Coli. BSND Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 290 amino acids (54-320) and having a molecular mass of 31.7kDa.BSND is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. BSND is a vital beta subunit for CLC chloride channels. These heteromeric channels are restricted to basolateral membranes of renal tubules and of potassium-secreting epithelia of the inner ear. BSND gene mutations are linked with Bartter syndrome with sensorineural deafness.
Product Specifications
Product Name Alternative
Bartter Syndrome Infantile With Sensorineural Deafness (Barttin) ||Deafness Autosomal Recessive 73||DFNB73||BART||barttin.
Purification
Greater than 90% as determined by SDS-PAGE.
Components
The BSND solution (0.25mg/mL) contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 1mM DTT and 10% glycerol.
Storage Conditions
Amino Acids
Frequently Asked Questions
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