BABAM1 Recombinant Protein
Source : Escherichia Coli. BABAM1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 352 amino acids (1-329 a.a.) and having a molecular mass of 38.9kDa.BABAM1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. BRISC And BRCA1 A Complex Member 1, also known as BABAM1, is a part of the BRCA1-A complex. The BRCA1-A complex identifies 'Lys-63'- linked ubiquitinated histones H2A and H2AX at DNA lesions sites and also holds deubiquitinase activity which removes in particular 'Lys-63'-linked ubiquitin on histones H2A and H2AX. BABAM1 is necessary to preserve the stability of BRE/BRCC45 and help the 'Lys-63'-linked deubiquitinase activity mediated by BRCC3/BRCC36 component.
Product Specifications
Product Name Alternative
Purification
Greater than 85% as determined by SDS-PAGE.
Components
BABAM1 protein solution (1mg/mL) containing 20mM Tris-HCl buffer (pH8.0), 10% glycerol and 0.1M NaCl.
Storage Conditions
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Avoid multiple freeze-thaw cycles.
Amino Acids
Frequently Asked Questions
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