STAT1 Recombinant Protein
Source : Escherichia Coli. STAT1 Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 732 amino acids (1-712 a.a.) and having a molecular mass of 85.2 kDa. The STAT1 is fused to 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques. STAT1 is a member of the Signal Transducers and Activators of Transcriptionfamily of transcription factors. STAT1 is involved in upregulating genes due to a signal by either type Ior type IIinterferons. In response to IFN-stimulation, STAT1 forms homodimers or heterodimers with STAT3that bind to the GAS (Interferon-Gamma Activated Sequence) promoter element; in response to either IFN- or IFN-stimulation, STAT1 forms a heterodimer with STAT2that can bind the ISRE (Interferon Stimulated Response Element) promoter element. In either case, binding of the promoter element leads to an increased expression of ISG (Interferon Stimulated Genes) .
Product Specifications
Product Name Alternative
Signal transducer and activator of transcription 1-alpha/beta||Transcription factor ISGF-3 components p91/p84||STAT1||ISGF-3||STAT91||DKFZp686B04100.
Purification
Greater than 90% as determined by SDS-PAGE.
Components
STAT1 0.5mg/mL protein solution contains 20mM Tris-HCl buffer pH-8, 0.1M Nacl, 1mM DTT and 10% glycerol.
Storage Conditions
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Avoid multiple freeze-thaw cycles.
Amino Acids
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
EEC2 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 1)
ABIN-1 (A-20 binding Inhibitor of Nuclear Factor-kappaB (NF-kB) Activation) (APC)
FAAH1 Polyclonal Antibody, AbBy Fluor™ 555 Conjugated