PRPS1 Recombinant Protein
Source : Escherichia Coli. PRPS1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 338 amino acids (1-318 a.a.) and having a molecular weight of 36.9kDa.The PRPS1 is fused to 20 a.a His-Tag at N-terminus and purified by proprietary chromatographic techniques. PRPS1 catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis. PRPS1 catalyzes the phosphoribosylation of ribose 5-phosphate to 5-phosphoribosyl-1-pyrophosphate, which is essential for purine metabolism and nucleotide biosynthesis. Defects in PRPS1 result in phosphoribosylpyrophosphate synthetase superactivity, Charcot-Marie-Tooth disease X-linked recessive type 5 and Arts Syndrome.
Product Specifications
Product Name Alternative
ARTS||CMTX5||PPRibP||PRSI||DFN2||Ribose-phosphate pyrophosphokinase 1||DFNX1||Phosphoribosyl pyrophosphate synthase I||PRS-I||PRPS1||KIAA0967.
Purification
Greater than 90.0% as determined by SDS-PAGE.
Components
The PRPS1 protein solution contains 20mM Tris-HCl, pH-8, 100mM NaCl, 1mM DTT and 20% glycerol.
Storage Conditions
Amino Acids
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