CIB2 Recombinant Protein

Source : Escherichia Coli. CIB2 Human Recombinant fused with a 20 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 207 amino acids (1-187a.a.) and having a molecular mass of 23.8kDa (Molecular weight on SDS-PAGE will appear higher) . The CIB2 is purified by proprietary chromatographic techniques. CIB2 is a member of the calcium and integrin-binding family.CIB2 is possibly a Ca2+-binding regulatory protein which interacts with DNA-dependent protein kinase catalytic subunit (DNA-PKcs) . In the skeletal muscle, CIB2 co-localizes with the integrin alpha7B subunit at the sarcolemma and at the neuromuscular and myotendinous junctions. CIB2 is closely related to CIB1.