Urokinase Native Protein

Source : Human urine. Urokinase is a two-chain glycoprotein containing 411 amino acids with 12 disulfide bonds. Its molecular weight is 54,000 Dalton. Urokinase (UK) is a serine protease, which is one of biological plasminogen activators. It is involved in a number of biological functions including fibrinolysis, embryogenesis, cell migration, tissue remodeling, ovulation, and wound healing. It can be obtained from human urine or kidney cell culture.

Product Specifications

Product Name Alternative

Urokinase||Abbokinase||Urokinase-type Plasminogen Activator, uPA||EC 3.4.21.73||UK.

Purification

Greater than 94.0% as determined by SDS-PAGE.

Components

The Urokinase was lyophilized from a concentrated (1mg/mL) solution containing phosphate buffer.

Storage Conditions

Lyophilized Urokinase although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Urokinase should be stored at 4°C between 2-7 days and for future use below -18°C.Please prevent freeze-thaw cycles.

Applications Notes

It is recommended to reconstitute the lyophilized Urokinase in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions.