UBE2D4 Recombinant Protein
Source : E.coli. UBE2D4 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 167 amino acids (1-147) and having a molecular mass of 18.8 kDa.UBE2D4 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. UBE2D4 is a member of the ubiquitin-conjugating enzyme family. Ubiquitin-conjugating enzymes (E2 enzymes or ubiquitin-carrier enzymes) execute the second step in the ubiquitination reaction which marks a protein for degradation using the proteasome. UBE2D4 receives ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro UBE2D4 can promote polyubiquitination using all 7 ubiquitin Lys residues, but usually selects 'Lys-11' and 'Lys-48'-linked polyubiquitination.
Product Specifications
Product Name Alternative
Ubiquitin-conjugating enzyme E2D 4 (putative) ||UBCH5D||HBUCE1||Ubiquitin carrier protein D4||Ubiquitin-protein ligase D4||EC 6.3.2.19.
Purification
Greater than 95% as determined by SDS-PAGE.
Components
The SRGN solution (1mg/mL) contains 20mM Tris-HCl buffer (pH 8.0), 2mM DTT, 0.1M NaCl and 10% glycerol.
Storage Conditions
Amino Acids
Frequently Asked Questions
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