PON1 Recombinant Protein

Source : Escherichia Coli. Paraoxonase-1 Isoform Human Recombinant is expressed in E. coli having a molecular weight of 42.9 kDa and fused to a 4.5kDa amino terminal hexahistidine tag.The PON1 purified by proprietary chromatographic techniques. Paraoxonase 1 also called Esterase-A is involved in the detoxification of organophosphate insecticides such as parathion. Paraoxonase 1 may also confer protection against coronary artery disease by destroying proinflammatory oxidized lipids present in oxidized low-density lipoproteins (LDLs) .

Product Specifications

Product Name Alternative

Serum paraoxonase||arylesterase 1||EC 3.1.1.2||EC 3.1.8.1||PON 1||Serum aryldialkylphosphatase 1||A-esterase 1||Aromatic esterase 1||K-45||ESA||PON.

Purification

Greater than 95% as determined by SDS-PAGE. Single band on Western Blot.

Components

PON1 is supplied in 20mM Tris-HCl pH 8.0 and 50% glycerol.

Storage Conditions

Store at 4°C if entire vial will be used within 1-2 weeks. Store, frozen at -20°C for longer periods of time. Avoid multiple freeze-thaw cycles.

Amino Acids

MAKLIALTLLGMGLALFRNHQSSYQTRLNALREVQPVELPNCNLVKGIETGSEDLEILPNGLAFISSGLKYPGIKSFNPNSPGKILLMDLNEEDPTVLELGITGSKFDVSSFNPHGISTFTDEDNAMYLLVVNHPDAKSTVELFKFQEEEKSLLHLKTIRHKLLPNLNDIVAVGPEHFYGTNDHYFLDPYLRSWEMYLGLAWSYVVYYSPSEVRVVAEGFDFANGINISPDGKYVYIAELLAHKIHVYEKHANWTLTPLKSLDFNTLVDNISVDPETGDLWVGCHPNGMKIFFYDSENPPASEVLRIQNILTEEPKVTQVYAENGTVLQGSTVASVYKGKLLIGTVFHKALYCELZ.