PGP Recombinant Protein

Source : Escherichia Coli. PGP produced in E.Coli is a single, non-glycosylated polypeptide chain containing 345 amino acids (1-321 a.a.) and having a molecular mass of 36.5kDa. PGP is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Phosphoglycolate phosphatase (PGP) is discovered in all tissues including red cells, lymphocytes and cultured fibroblasts (at protein level) . PGP is most active in skeletal muscle and cardiac muscle. The catalytic activity of PGP is 2-phosphoglycolate + H2O = glycolate + phosphate. Diseases associated with PGP include tardive dyskinesia and polycystic kidney disease.