N6AMT1 Recombinant Protein

Source : E.coli. N6AMT1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 237 amino acids (1-214 a.a) and having a molecular mass of 25.3kDa. N6AMT1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. N-6 Adenine-Specific DNA Methyltransferase 1, also known as N6AMT1 is part of the methyltransferase family. N6AMT1 is implicated in the methylation of release factor I during translation termination. In addition, N6AMT1 is involved in converting the arsenic metabolite monomethylarsonous acid to the less toxic dimethylarsonic acid.

Product Specifications

Product Name Alternative

N-6 Adenine-Specific DNA Methyltransferase 1 (Putative) ||N (6) -Adenine-Specific DNA Methyltransferase 1||HemK Methyltransferase Family Member 2||M.HsaHemK2P||C21orf127, HEMK2||Chromosome 21 Open Reading Frame 127||N6-DNA-Methyltransferase||EC 2.1.1.-

Purification

Greater than 85% as determined by SDS-PAGE.

Components

N6AMT1 protein solution (0.25 mg/mL) containing Phosphate buffered saline (pH7.4), 20% glycerol and 1mM DTT.

Storage Conditions

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) .Avoid multiple freeze-thaw cycles.

Amino Acids

MGSSHHHHHH SSGLVPRGSH MGSMAGENFA TPFHGHVGRG AFSDVYEPAE DTFLLLNALE AAAAELAGVEICLEVGSGSG VVSAFLASMI GPQALYMCTD INPEAAACTL ETARCNKVHI QPVITDLVKG LLPRLTEKVDLLVFNPPYVV TPPQEVGSHG IEAAWAGGRN GREVMDRFFPLVPDLLSPRG LFYLVTIKEN NPEEILKIMK TKGLQGTTAL SRQAGQETLSVLKFTKS.