NRG4 Recombinant Protein
Source : Escherichia Coli. NRG4 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 84 amino acids (1-61 a.a.) and having a molecular mass of 9.1kDa. NRG4 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Neuregulin-4 (NRG4) is a part of the neuregulin family that owns 1 EGF-like domain and is a low affinity ligand for the ERBB4 tyrosine kinase receptor. NRG4 links ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors.
Product Specifications
Product Name Alternative
Neuregulin 4||HRG4||Pro-neuregulin-4||membrane-bound isoform||Pro-NRG4||NRG-4.
Purification
Greater than 90% as determined by SDS-PAGE.
Components
NRG4 protein solution (0.25mg/mL) contains 20mM Tris-HCl (pH8.0), 30% glycerol, 0.15M NaCl and 1mM DTT.
Storage Conditions
Amino Acids
MGSSHHHHHH SSGLVPRGSH MGSMPTDHEE PCGPSHKSFC LNGGLCYVIP TIPSPFCRCV ENYTGARCEE VFLPGSSIQT KSNL.
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