IL 18 His Recombinant Protein
Source : Escherichia Coli. Interleukin-18 Human Recombinant produced in E.Coli is a single, non-glycosylated, Polypeptide chain containing 157 amino acids fragment (37-193) having a molecular weight of 20kDa and fused with a 4.5kDa amino-terminal hexahistidine tag. The IL-18 His is purified by proprietary chromatographic techniques. IL-18 is a proinflammatory cytokine. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL-18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity.
Product Specifications
Product Name Alternative
Interferon-gamma-inducing factor||IGIF||IL-1g||IL-18||IL1F4||MGC12320||IFN-gamma-inducing factor||Interleukin-1 gamma||IL-1 gamma||Iboctadekin||IL18.
Purification
Greater than 95.0% as determined by SDS-PAGE.
Components
Interleukin -18 His-Tag protein is supplied in 20mM Tris-HCl pH-8 and 50% glycerol.
Storage Conditions
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles.
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