MIFNB Recombinant Protein

Source : Escherichia Coli. Interferon beta Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 182 amino acids (22-182 a.a.) and having a molecular mass of 22 kDa. Mouse IFN beta is fused to 20 amino acid at N-terminus and purified by proprietary chromatographic techniques. Interferon-beta 1b has antiviral, antibacterial and anticancer activities.Influenza A viruses not only inhibit IFN-beta gene induction but also supress Type-I IFN signaling via mechanism involving induction of the SOCS-3 protein.Intracellular bacteria and cytosolic poly (dA-dT) trigger IFN-beta responses in different human cells without requiring human ZBP1.

Product Specifications

Product Name Alternative

Leukocyte interferon||B cell interferon||Type I interferon||IFNB1||IFB||IFF||IFNB||IFN-b 1b||MGC96956.

Purification

Greater than 95% as determined by Analysis by SDS-PAGE.

Components

The IFN-Beta (0.25mg/mL) contains 20mM HEPES (pH6.0), 0.5M NaCl, 10% glycerol.

Storage Conditions

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) . Avoid multiple freeze-thaw cycles.

Amino Acids

MGSSHHHHHH SSGLVPRGSH MINYKQLQLQ ERTNIRKCQE LLEQLNGKIN LTYRADFKIP MEMTEKMQKS YTAFAIQEML QNVFLVFRNN FSSTGWNETI VVRLLDELHQ QTVFLKTVLE EKQEERLTWE MSSTALHLKS YYWRVQRYLK LMKYNSYAWM VVRAEIFRNF LIIRRLTRNF QN.