3,5-Di-tert-butylphenol

3,5-Di-tert-butylphenol is an volatile organic compound with anti-biofilm and antifungal activities. 3,5-Di-tert-butylphenol induces accumulation of reactive oxygen species (ROS) in C. albicans cells. 3,5-Di-tert-butylphenol also has antibacterial activities[1][2].

Product Specifications

CAS Number

[1138-52-9]

UNSPSC

12352005

Hazard Statement

H314, H318, H413

Target

Bacterial; Fungal; Reactive Oxygen Species (ROS)

Type

Natural Products

Related Pathways

Anti-infection; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/3-5-di-tert-butylphenol.html

Purity

99.98

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

OC1=CC(C(C)(C)C)=CC(C(C)(C)C)=C1

Molecular Formula

C14H22O

Molecular Weight

206.33

Precautions

H314, H318, H413

References & Citations

[1]Janarthanam Rathna, et al. Anti-biofilm mechanisms of 3,5-di-tert-butylphenol against clinically relevant fungal pathogens. Biofouling. 2016 Oct;32 (9) :979-93.|[2]Rouvier F, et al. Identification of 2,4-Di-tert-Butylphenol as an Antimicrobial Agent Against Cutibacterium acnes Bacteria from Rwandan Propolis. Antibiotics (Basel) . 2024 Nov 13;13 (11) :1080.