Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Nav1.7-IN-3

Nav1.7-IN-3 is a selective, orally bioavailable voltage-gated sodium channel Nav1.7 inhibitor with an IC50 of 8 nM. Pain relief. Limited CNS penetration[1].

Product Specifications

CAS Number

1788872-06-9

UNSPSC

12352005

Target

Sodium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Nav1.7-IN-3.html

Purity

98.21

Solubility

DMSO : < 1 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

FC1=C(S(=O)(NC2=NC=CS2)=O)C=C(Cl)C(NCC34CCCN3CCC4)=C1

Molecular Formula

C17H20ClFN4O2S2

Molecular Weight

430.95

References & Citations

[1]Roecker AJ, et al. Discovery of selective, orally bioavailable, N-linked arylsulfonamide Nav1.7 inhibitors with pain efficacy in mice. Bioorg Med Chem Lett. 2017 May 15;27 (10) :2087-2093.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Nav1.7

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Uncoated Human IL-15 (Interleukin 15) ELISA Kit
E-UNEL-H0387-01 5x 96 Tests

Uncoated Human IL-15 (Interleukin 15) ELISA Kit

Sign In for Pricing
View Details
Uncoated Human IL-15 (Interleukin 15) ELISA Kit
E-UNEL-H0387-02 15x 96 Tests

Uncoated Human IL-15 (Interleukin 15) ELISA Kit

Sign In for Pricing
View Details
ZRANB2 antibody
FNab09755 100 µg

ZRANB2 antibody

Sign In for Pricing
View Details
Elab Fluor® 647 Anti-Mouse CD11a Antibody[FD441.8]
E-AB-F1033M-01 50 Tests

Elab Fluor® 647 Anti-Mouse CD11a Antibody[FD441.8]

Sign In for Pricing
View Details
Elab Fluor® 647 Anti-Mouse CD11a Antibody[FD441.8]
E-AB-F1033M-02 100 Tests

Elab Fluor® 647 Anti-Mouse CD11a Antibody[FD441.8]

Sign In for Pricing
View Details
Elab Fluor® 647 Anti-Mouse CD11a Antibody[FD441.8]
E-AB-F1033M-03 2x 100 Tests

Elab Fluor® 647 Anti-Mouse CD11a Antibody[FD441.8]

Sign In for Pricing
View Details