Biotinylated Rabbit Monoclonal Antibody to Pembrolizumab (Clone : 90G12F8)
Pembrolizumab (Keytruda) is a humanized monoclonal antibody that is approved by the U.S. Food and Drug Administration for the treatment of patients with unresectable or metastatic melanoma. Pembrolizumab binds to the human cell surface receptor PD-1 (Programmed Cell Death Protein 1) and blocks its interaction with PD-L1, resulting in the activation of T-cell-mediated immune responses against tumor cells. Anti-Pembrolizumab Antibody (90G12F8) [BIOTIN], mAb, Rabbit is produced from a hybridoma resulting from the fusion of partner and B-lymphocytes obtained from a rabbit immunized with Pembrolizumab.
Product Specifications
Host
Rabbit
Immunogen
Pembrolizumab
Clonality
Monoclonal
Clone
90G12F8
Applications
ELISA
Purification
Protein A chromatography
Format
Purified
Components
0.5 mg/mL, lyophilized with PBS, pH 7.4, containing 0.02% sodium azide.
Storage Conditions
Applications Notes
ELISA detection: 0.01-0.1 ‚μg/mL ELISA blocking: 10-50 ‚μg/mL
Isotype
Rabbit IgG
Conjugate
Biotin
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