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Biotinylated Rabbit Monoclonal Antibody to Pembrolizumab (Clone : 90G12F8)

Pembrolizumab (Keytruda) is a humanized monoclonal antibody that is approved by the U.S. Food and Drug Administration for the treatment of patients with unresectable or metastatic melanoma. Pembrolizumab binds to the human cell surface receptor PD-1 (Programmed Cell Death Protein 1) and blocks its interaction with PD-L1, resulting in the activation of T-cell-mediated immune responses against tumor cells. Anti-Pembrolizumab Antibody (90G12F8) [BIOTIN], mAb, Rabbit is produced from a hybridoma resulting from the fusion of partner and B-lymphocytes obtained from a rabbit immunized with Pembrolizumab.

Product Specifications

Host

Rabbit

Immunogen

Pembrolizumab

Clonality

Monoclonal

Clone

90G12F8

Applications

ELISA

Purification

Protein A chromatography

Format

Purified

Components

0.5 mg/mL, lyophilized with PBS, pH 7.4, containing 0.02% sodium azide.

Storage Conditions

The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.

Applications Notes

ELISA detection: 0.01-0.1 ‚μg/mL ELISA blocking: 10-50 ‚μg/mL

Isotype

Rabbit IgG

Conjugate

Biotin

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