Mouse Monoclonal Antibody to Nivolumab (Clone : 8G6G3D8)
Nivolumab (Opdivo) is a humanized monoclonal antibody that is approved by the U.S. Food and Drug Administration for the treatment of patients with unresectable or metastatic melanoma. Nivolumab binds to the human cell surface receptor PD-1 (Programmed Cell Death Protein 1) and blocks its interaction with PD-L1, resulting in the activation of T-cell-mediated immune responses against tumor cells. Anti-Nivolumab Antibody (8G6G3D8), mAb, Mouse is produced from a hybridoma resulting from the fusion of partner and B-lymphocytes obtained from a mouse immunized with Nivolumab.
Product Specifications
Host
Mouse
Immunogen
Nivolumab
Clonality
Monoclonal
Clone
8G6G3D8
Applications
ELISA
Purification
Protein A chromatography
Format
Purified
Components
0.5 mg/mL, lyophilized with PBS, pH 7.4, containing 0.02% sodium azide.
Storage Conditions
Applications Notes
ELISA detection: 0.01-0.1 μg/mL
Isotype
Mouse IgG1
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