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Anti-p57 kip2 Monoclonal Antibody (Clone:IHC057)

P57kip2, also known as p57, is a tumor suppressor protein that causes cell cycle arrest at G1 by binding G1 cyclin-CDK complexes. The p57kip2 gene is a potential tumor suppressor target as the gene is located in a chromosomal region implicated in sporadic cancers, Wilms' tumor, and Beckwith Wiedemann syndrome. Anti-p57kip2 labels many cytotrophoblast nuclei and stromal cells in normal placenta, and is useful in differentiating between complete hydatidiform mole and partial hydatidiform mole or hydropic abortion.

Product Specifications

Product Name Alternative

KIP2, Cyclin-dependent kinase inhibitor p57, p57Kip2

Gene Name

CDKN1C

Gene ID

1028

UniProt

P49918

Host

Mouse

Reactivity

Human

Clonality

Monoclonal

Clone

IHC057

Applications

IHC

Purification

Protein A/G Chromatography

Format

Purified

Shipping Conditions

Blue Ice / Ice Pack

Storage Conditions

Store at 2°C - 8°C.

Applications Notes

Recommended dilutions: Immunohistochemical analysis: 1:100 - 1:200. However, this need to be optimized based on the research applications.

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