Anti-p57 kip2 Monoclonal Antibody (Clone:IHC057)
P57kip2, also known as p57, is a tumor suppressor protein that causes cell cycle arrest at G1 by binding G1 cyclin-CDK complexes. The p57kip2 gene is a potential tumor suppressor target as the gene is located in a chromosomal region implicated in sporadic cancers, Wilms' tumor, and Beckwith Wiedemann syndrome. Anti-p57kip2 labels many cytotrophoblast nuclei and stromal cells in normal placenta, and is useful in differentiating between complete hydatidiform mole and partial hydatidiform mole or hydropic abortion.
Product Specifications
Product Name Alternative
KIP2, Cyclin-dependent kinase inhibitor p57, p57Kip2
Gene Name
CDKN1C
Gene ID
1028
UniProt
P49918
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Clone
IHC057
Applications
IHC
Purification
Protein A/G Chromatography
Format
Purified
Shipping Conditions
Blue Ice / Ice Pack
Storage Conditions
Store at 2°C - 8°C.
Applications Notes
Recommended dilutions: Immunohistochemical analysis: 1:100 - 1:200. However, this need to be optimized based on the research applications.
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