Anti-SOX-10 Monoclonal Antibody (Clone:IHC010)
SRY (Sex Determining Region Y) -Box 10 (SOX-10), also known as transcription factor SOX-10, is a nuclear transcription factor that acts in regulation of embryonic development and in the specification and differentiation of cells of melanocytic lineage. SOX-10 is diffusely expressed in neurofibromas and schwannomas, and mutations in the SOX-10 gene are linked to Waardenburg-Shah and Waardenburg-Hirschsprung disease. Anti-SOX-10 has been shown to be sensitive for conventional, spindled, and desmoplastic melanoma, and has been used to detect metastatic melanoma and nodal capsular nevus in sentinel lymph nodes.
Product Specifications
Product Name Alternative
SOX10
Gene Name
SOX10
Gene ID
6663
UniProt
P56693
Host
Mouse
Reactivity
Human
Immunogen
Recombinant Human SOX-10
Clonality
Monoclonal
Clone
IHC010
Applications
IHC
Purification
Protein A/G Chromatography
Format
Purified
Components
Tris Buffer, pH 7.3 - 7.7, with 1% BSA and
Storage Conditions
Store at 2°C - 8°C. Do not freeze.
Applications Notes
Recommended dilutions: Immunohistochemical analysis: 1:100 - 1:200. However, this need to be optimized based on the research applications.
Frequently Asked Questions
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