Anti-PAX-8 Monoclonal Antibody (Clone:IHC008)
PAX-8 is a member of the paired box (PAX) family of transcription factors, which are key regulators in early development. This protein plays a role in development of thyroid follicular cells and the expression of thyroid-specific genes, with mutations in the PAX-8 gene linked to thyroid follicular carcinomas, atypical thyroid adenomas, and thyroid dysgenesis. The PAX-8 protein is expressed in simple ovarian inclusion cysts and non-ciliated mucosal cells of the fallopian tubes, but is absent from normal ovarian surface epithelial cells. PAX-8 is also not expressed in normal lung or lung carcinomas.
Product Specifications
Product Name Alternative
PAX8
Gene Name
PAX8
Gene ID
7849
UniProt
Q06710
Host
Mouse
Reactivity
Human
Immunogen
Recombinant Human PAX8
Clonality
Monoclonal
Clone
IHC008
Applications
IHC
Purification
Protein A/G Chromatography
Format
Purified
Components
Tris Buffer, pH 7.3 - 7.7, with 1% BSA and
Storage Conditions
Store at 2°C - 8°C. Do not freeze.
Applications Notes
Recommended dilutions: Immunohistochemical analysis: 1:100 - 1:200. However, this need to be optimized based on the research applications.
Isotype
Mouse IgG2a
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