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Anti-CD138 Monoclonal Antibody (Clone:IHC138)

Cluster of differentiation 138 (CD138), also known as Syndecan-1, is a transmembrane glycoprotein present on the surface of B-cells during late stage differentiation. Anti-CD138 is used to differentiate marginal zone lymphoma from lymphoplasmacytic lymphoma. ALK+ Large B-Cell Lymphoma (LBCL) commonly stains positively for CD138, but not for CD20 and CD79a. Anti-CD138 reacts positively with HHV8-associated primary effusion lymphoma that lack B-cell markers. CD138 is also a useful marker for identifying and enumerating benign, reactive, or malignant plasma cells from the bone marrow biopsy samples.

Product Specifications

Product Name Alternative

SDC1||SDC

Gene Name

SDC1

Gene ID

6382

UniProt

P18827

Host

Mouse

Reactivity

Human

Immunogen

Recombinant Human CD138

Clonality

Monoclonal

Clone

IHC138

Applications

IHC

Purification

Protein A/G Chromatography

Format

Purified

Components

Tris Buffer, pH 7.3 - 7.7, with 1% BSA and

Storage Conditions

Store at 2°C - 8°C. Do not freeze.

Applications Notes

Recommended dilutions: Immunohistochemical analysis: 1:100 - 1:200. However, this need to be optimized based on the research applications.

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