Anti-BSEP Monoclonal Antibody (Clone:IHC518)
Bile Salt Export Pump (BSEP) is a member of the ATP-binding cassette (ABC) transporters, which mediates the transport of bile acid, taurocholate and other cholate conjugates across the hepatocyte canalicular membrane into the canaliculus. BSEP is associated with progressive familial intrahepatic cholestasis type 2 (PFIC2) and benign recurrent intrahepatic cholestasis type 2 (BRIC2) . PFIC2 caused by mutations in the BSEP gene increases the risk of hepatocellular carcinoma in early life
Product Specifications
Product Name Alternative
ABCB11||BSEP
Gene Name
ABCB11
Gene ID
8647
UniProt
O95342
Host
Mouse
Reactivity
Human
Immunogen
Recombinant Human BSEP
Clonality
Monoclonal
Clone
IHC518
Applications
IHC
Purification
Protein A/G Chromatography
Format
Purified
Components
Tris Buffer, pH 7.3 - 7.7, with 1% BSA and
Storage Conditions
Store at 2°C - 8°C. Do not freeze.
Applications Notes
Recommended dilutions: Immunohistochemical analysis: 1:100 - 1:200. However, this need to be optimized based on the research applications.
Isotype
Mouse IgG1
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