Polyclonal Antibody to CD134/OX40/TNFRSF4

Tumor necrosis factor receptor superfamily, member 4, also known as ACT35 or CD134, is a cell surface glycoprotein that was discovered through the production of a monoclonal antibody raised against the HUT-102 cell line. It belongs to the tumor necrosis factor receptor superfamily. CD134 was mapped to 1p36 by fluorescence in situ hybridization. CD134 is the primary receptor for feline immunodeficiency virus. And CD134 expression can promote viral binding and renders cells permissive for viral entry, productive infection, and syncytium formation. Stimulating the receptor can improve the response to a powerful virus vector and may be useful in vaccine development.

Product Specifications

Product Name Alternative

Tumor necrosis factor receptor superfamily member 4, ACT35 antigen, OX40L receptor, TAX

Gene Name

TNFRSF4

Gene ID

7293

UniProt

P43489

Host

Rabbit

Reactivity

Human

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human CD134/OX40 (232-254aa AILLALYLLRRDQRLPPDAHKPP), different from the related mouse sequence by ten amino acids.

Target Antigen

OX40

Clonality

Monoclonal

Applications

ICC, IHC, FACS, WB

Components

Each vial contains BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Storage Conditions

At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid repeated freezing and thawing.

Applications Notes

Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, By Heat; Western blot, 0.1-0.5μg/ml; Immunohistochemistry (Frozen Section) -0.5-1μg/ml; Immunocytochemistry, 0.5-1μg/ml; Flow Cytometry, 1-3μg/1x106 cells