Anti-IL18 Polyclonal Antibody

Interleukin (IL) -18, also called Interferon-gamma-inducing factor (IGIF), augments natural killer (NK) activity in spleen cells. The gene encodes a precursor protein of 192 amino acids and a mature protein of 157 amino acids. IL18 is a recently discovered cytokine that modulates both T helper type 1 (Th1) and Th2 responses. IL18 is a potent proinflammatory cytokine with potential atherogenic properties. It is highly expressed in the atherosclerotic plaques compared with control normal arteries and is localized mainly in plaque macrophages.

Product Specifications

Product Name Alternative

Interleukin-18; IL-18; Interferon gamma-inducing factor; IFN-gamma-inducing factor; Interleukin-1 gamma; IL-1 gamma; Il18; Igif

Gene Name

Il18

Gene ID

29197

UniProt

P97636

Host

Rabbit

Reactivity

Rat

Immunogen

E.coli-derived rat IL18 recombinant protein (Position: H37-S194) . Rat IL18 shares 64% and 91% amino acid (aa) sequence identity with human and mouse IL18, respectively.

Target Antigen

Interleukin-18

Clonality

Polyclonal

Applications

Purification

Immunogen affinity purified.

Components

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3. Reconstitute : Add 0.2ml of distilled water will yield a concentration of 500ug/mL.

Storage Conditions

At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.