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Anti-IL2 Polyclonal Antibody

Interleukin-2 (IL2), formerly referred to as T-cell growth factor, is a powerfully immunoregulatory lymphokine that is produced by lectin- or antigen-activated T cells. It is produced not only by mature T lymphocytes on stimulation but also constitutively by certain T-cell lymphoma cell lines. The lymphokine interleukin-2 (IL-2) is responsible for autocrine cell cycle progression and regulation of immune responses. IL-2 expression in mature thymocytes and T cells has been found to be tightly controlled by monoallelic expression. IL-2 can act as a growth hormone for both B and T lymphocytes. This gene for interleukin 2 (IL2) is assigned to chromosome 4. IL-2 is a 15.5KDa glycoprotein, consisting of 153 amino acids in precursor form and 133 amino acids in mature form.

Product Specifications

Product Name Alternative

Interleukin-2; IL-2; T-cell growth factor; TCGF; Il2; Il-2

Gene Name

Il2

Gene ID

116562

UniProt

P17108

Host

Rabbit

Reactivity

Rat

Immunogen

E.coli-derived rat IL2 recombinant protein (Position: A21-Q155) . Rat IL2 shares 66% and 80% amino acid (aa) sequence identity with human and mouse IL2, respectively.

Target Antigen

Interleukin-2

Clonality

Polyclonal

Applications

WB

Purification

Immunogen affinity purified.

Format

Lyophilized

Components

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3. Reconstitute : Add 0.2ml of distilled water will yield a concentration of 500ug/mL.

Storage Conditions

At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

Applications Notes

Western blot : 0.1-0.5μg/ml

Isotype

Rabbit IgG

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