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Anti-Kv1.1 potassium channel Polyclonal Antibody

Potassium voltage-gated channel subfamily A member 1, also known as Kv1.1, is a shaker related voltage-gated potassium channel that in humans is encoded by the KCNA1 gene. It is mapped to 12p13.32. The protein functions as a potassium selective channel through which the potassium ion may pass through in consensus with the electrochemical gradient. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting.

Product Specifications

Product Name Alternative

Potassium voltage-gated channel subfamily A member 1; Voltage-gated K (+) channel HuKI ; Voltage-gated potassium channel HBK1 ; Voltage-gated potassium channel subunit Kv1.1; KCNA1

Gene Name

KCNA1

Gene ID

3736

UniProt

Q09470

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human Kv1.1 potassium channel (465-481aa IAHYRQVNIRTANCTTA), different from the related mouse sequence by two amino acids, and from the related rat sequence by four amino acids .

Target Antigen

Potassium voltage-gated channel subfamily A member 1

Clonality

Polyclonal

Applications

WB

Purification

Immunogen affinity purified.

Format

Lyophilized

Components

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitute : Add 0.2ml of distilled water will yield a concentration of 500ug/mL.

Storage Conditions

At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

Applications Notes

Western blot : 0.1-0.5μg/ml

Isotype

Rabbit IgG

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