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Anti-Cdk4 Polyclonal Antibody

Cyclin-dependent kinase-4 (CDK4) is a protein-serine kinase involved in the cell cycle. Human cell division is regulated primarily at the G1-to-S or the G2-to-M boundaries within the cell cycle. The complexes formed by CDK4 and the D-type cyclins are involved in the control of cell proliferation during the G1 phase. CDK4 is inhibited by p16, also known as cyclin-dependent kinase inhibitor-2. CDK4 is mapped to 12q14. CDK4 expression and activity are required for cytokine responsiveness in T cells.

Product Specifications

Product Name Alternative

Cyclin-dependent kinase 4; 2.7.11.22; CRK3; Cell division protein kinase 4; PSK-J3; Cdk4; Crk3

Gene Name

Cdk4

Gene ID

12567

UniProt

P30285

Host

Rabbit

Reactivity

Human

Target Antigen

Cyclin-dependent kinase 4

Clonality

Polyclonal

Applications

WB

Purification

Immunogen affinity purified.

Components

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitute : Add 0.2ml of distilled water will yield a concentration of 500ug/mL.

Storage Conditions

At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

Applications Notes

Western blot : 0.1-0.5μg/ml

Isotype

Rabbit IgG

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