Anti-TIMP4 Polyclonal Antibody

Metalloproteinase inhibitor 4 is an enzyme that in humans is encoded by the TIMP4 gene. And this gene is mapped to chromosome 3p25. This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. The secreted, netrin domain-containing protein encoded by this gene is involved in regulation of platelet aggregation and recruitment and may play role in hormonal regulation and endometrial tissue remodeling.

Product Specifications

Product Name Alternative

Metalloproteinase inhibitor 4; Tissue inhibitor of metalloproteinases 4; TIMP-4; TIMP4

Gene Name

TIMP4

Gene ID

7079

UniProt

Q99727

Host

Rabbit

Reactivity

Human, Rat

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human TIMP4 (208-224aa YRGHLPLRKEFVDIVQP), different from the related rat sequence by two amino acids, and from the related mouse sequence by three amino acids.

Target Antigen

Metalloproteinase inhibitor 4

Clonality

Polyclonal

Applications

WB, IHC-P

Purification

Immunogen affinity purified.

Format

Lyophilized

Components

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitute : Add 0.2ml of distilled water will yield a concentration of 500ug/mL.