Anti-CD40 Polyclonal Antibody
CD40 is a cell surface receptor that is expressed on the surface of all mature B cells and also expressed on monocytes, dendritic cells, and thymic epithelium. CD40 is a member of the tumor necrosis factor (TNF) receptor superfamily and is the receptor for CD40 ligand. CD40 ligand (CD40L, CD154, gp39, and TRAM) belongs to the TNF gene family and is expressed more widely than CD40 predominantly on activated CD4+ T cells. Activation of CD40 has also been shown to inhibit the growth of certain B cell lymphomas and to induce the death of transformed cells of mesenchymal or epithelial origin.
Product Specifications
Product Name Alternative
Tumor necrosis factor receptor superfamily member 5; B-cell surface antigen CD40; Bp50; CD40L receptor; CDw40; CD40; CD40; TNFRSF5
Gene Name
CD40
Gene ID
958
UniProt
P25942
Host
Rabbit
Reactivity
Mouse
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of mouse CD40 (22-36aa, QCVTCSDKQYLHDGQ) .
Target Antigen
Tumor necrosis factor receptor superfamily member 5
Clonality
Polyclonal
Applications
WB
Purification
Immunogen affinity purified.
Format
Lyophilized
Components
Storage Conditions
At -20°C for one year, at 4°C for one month. Avoid repeated freezing and thawing.
Applications Notes
Western blot : 0.1-0.5μg/ml
Isotype
Rabbit IgG
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