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Anti-BDNF Polyclonal Antibody

Brain derived neurotrophic factor (BDNF) is a member of the neurotrophin family of growth factors that includes NGF, NT3, and NT4. BDNF is a prosurvival factor induced by cortical neurons that is necessary for survival of striatal neurons in the brain. BDNF is expressed within peripheral ganglia and is not restricted to neuronal target fields. BDNF has been purified and shown to reduce the amount of naturally occurring neuronal cell death in portions of the peripheral nervous system.

Product Specifications

Product Name Alternative

Brain-derived neurotrophic factor; BDNF; Abrineurin; BDNF

Gene Name

BDNF

Gene ID

627

UniProt

P23560

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminal of human BDNF (129-148aa HSDPARRGELSVCDSISEWV), identical to the related rat and mouse sequences.

Target Antigen

Brain-derived neurotrophic factor (BDNF)

Clonality

Polyclonal

Applications

WB

Purification

Immunogen affinity purified.

Format

Lyophilized

Components

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitute : Add 0.2ml of distilled water will yield a concentration of 500ug/mL.

Storage Conditions

At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

Applications Notes

Western blot : 0.1-0.5μg/ml

Isotype

Rabbit IgG

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