Anti-FOXP3 Polyclonal Antibody

FOXP3 (forkhead box P3) is a protein involved in immune system responses. The human FOXP3 genes contain 11 coding exons. Exon-intron boundaries are identical across the coding regions of the mouse and human genes. By genomic sequence analysis, the FOXP3 gene maps to the p arm of the X chromosome (specifically, Xp11.23) . A member of the FOX protein family, FOXP3 appears to function as a master regulator in the development and function of regulatory T cells. While the precise control mechanism has not yet been established, FOX proteins belong to the forkhead/winged-helix family of transcriptional regulators and are presumed to exert control via similar DNA binding interactions during transcription.

Product Specifications

Product Name Alternative

Forkhead box protein P3; Scurfin; Forkhead box protein P3, C-terminally processed; Forkhead box protein P3 41 kDa form; FOXP3; IPEX; JM2

Gene Name

FOXP3

Gene ID

50943

UniProt

Q9BZS1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

E.coli-derived Human FOXP3 recombinant protein (Position: H101-P431) . Human FOXP3 shares 88% amino acid (aa) sequence identity with Mouse FOXP3.

Target Antigen

Forkhead box protein P3

Clonality

Polyclonal

Applications

IHC-P

Purification

Immunogen affinity purified.

Format

Lyophilized

Components

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3. Reconstitute : Add 0.2ml of distilled water will yield a concentration of 500ug/mL.

Storage Conditions

At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.