Anti-FOXP3 Polyclonal Antibody
FOXP3 (forkhead box P3) is a protein involved in immune system responses. The human FOXP3 genes contain 11 coding exons. Exon-intron boundaries are identical across the coding regions of the mouse and human genes. By genomic sequence analysis, the FOXP3 gene maps to the p arm of the X chromosome (specifically, Xp11.23) . A member of the FOX protein family, FOXP3 appears to function as a master regulator in the development and function of regulatory T cells. While the precise control mechanism has not yet been established, FOX proteins belong to the forkhead/winged-helix family of transcriptional regulators and are presumed to exert control via similar DNA binding interactions during transcription.
Product Specifications
Product Name Alternative
Forkhead box protein P3; Scurfin; Forkhead box protein P3, C-terminally processed; Forkhead box protein P3 41 kDa form; FOXP3; IPEX; JM2
Gene Name
FOXP3
Gene ID
50943
UniProt
Q9BZS1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
E.coli-derived Human FOXP3 recombinant protein (Position: H101-P431) . Human FOXP3 shares 88% amino acid (aa) sequence identity with Mouse FOXP3.
Target Antigen
Forkhead box protein P3
Clonality
Polyclonal
Applications
IHC-P
Purification
Immunogen affinity purified.
Format
Lyophilized
Components
Storage Conditions
Applications Notes
Immunohistochemistry (Paraffin-embedded Section) : 0.5-1μg/ml
Isotype
Rabbit IgG
Frequently Asked Questions
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