Anti-Talin Monoclonal Antibody (Clone: 8d4)
Talin is a high-molecular-weight cytoskeletal protein concentrated at regions of cell-substratum contact and, in lymphocytes, at cell-cell contacts. Talin serves a function of linking vinculin to the integrins, and, thus, the cytoskeleton to extracellular matrix (ECM) receptors. It has a mass of 270 kD and shares 23% N-terminal identity with ezrin, which has similar functions. TLN gene is mapped to 9p.
Product Specifications
Product Name Alternative
Protein Tln2 ; Tln2
Gene Name
Tln2
UniProt
D3ZA84
Host
Mouse
Reactivity
Human
Immunogen
Purified chicken gizzard talin.
Target Antigen
Talin-1; Talin-2
Clonality
Monoclonal
Clone
8d4
Applications
WB
Purification
Ascites
Components
Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative. Reconstitute : Add 1ml of PBS buffer will yield a concentration of 100ug/mL.
Storage Conditions
At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
Applications Notes
Western blot : 2-4μg/ml
Isotype
Mouse IgG1
Curated Selection
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