Anti-PKB alpha Monoclonal Antibody (Clone: PKB-175)
Selected Variant
39-1088-100
Size: 100 µg/Vial
PKB alpha also knows as V-AKT murine thymoma vial oncogene homolog 1 (ATK1) . AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and is abrogated by mutations in the pleckstrin homology domain of AKT1. AKT1 gene is mapped to chromosome 14q32.3. Akt1/protein kinase B-alpha is critical for ischemic and VEGF-mediated angiogenesis. Akt1 regulates pathological angiogenesis, vascular maturation and permeability in vivo.
Product Specifications
Product Name Alternative
RAC-alpha serine/threonine-protein kinase; 2.7.11.1; Protein kinase B; PKB; Protein kinase B alpha; PKB alpha; RAC-PK-alpha; Akt1
Gene Name
Akt1
Gene ID
24185
UniProt
P47196
Host
Mouse
Reactivity
Human
Immunogen
Synthetic peptide corresponding to amino acids 461-477 of human PKB alpha/Akt1, conjugated to KLH.
Target Antigen
RAC-alpha serine/threonine-protein kinase
Clonality
Monoclonal
Clone
PKB-175
Applications
WB
Purification
Ascites
Components
Storage Conditions
Applications Notes
Western blot : 0.25-0.5μg/ml
Isotype
Mouse IgG1
Price
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