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Anti-beta-HCG Monoclonal Antibody (Clone: PC-2)

Beta-HCG (beta-Human Chorionic Gonadotropin), also termed as Chorionic Gonadotropin, Beta Chain (CGB) . It is encoded by a multigene cluster composed of six homologous sequences. And in the family of beta-containing glycoprotein hormones, beta-HCG is unique in that it contains an extension of 29 amino acids at its COOH end. beta-HCG is mapped to 19q13.32 and expressed in trophoblast and various malignant tumors promotes cellular motility in vivo. beta-HCG has a novel function in uterine adaptation to early pregnancy as well as in tumor development and underline the importance of HCG as an as yet unrecognized angiogenic factor.

Product Specifications

Product Name Alternative

Choriogonadotropin subunit beta; CG-beta; Chorionic gonadotrophin chain beta; CGB; CGB3; CGB5; CGB7; CGB8

Gene Name

CGB3

Gene ID

1082

UniProt

P0DN86

Host

Mouse

Reactivity

Human

Immunogen

Purified human Chorionic Gonadotropin.

Target Antigen

Choriogonadotropin subunit beta

Clonality

Monoclonal

Clone

PC-2

Applications

IHC-P

Purification

Ascites

Components

Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative. Reconstitute : Add 1ml of PBS buffer will yield a concentration of 100ug/mL.

Storage Conditions

At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

Applications Notes

Immunohistochemistry (Paraffin-embedded Section) : 2μg/ml

Isotype

Mouse IgG1

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