Anti-alpha-Adaptin Monoclonal Antibody (Clone: 100/2)

Alpha Adaptin, also known as adaptor related protein complex, alpha 1 subunit. The alpha adaptins are exclusively found in the endocytic coated vesicles. Huntingtin-interacting protein 1 (HIP1) is enriched in membrane-containing cell fractions and has been implicated in vesicle trafficking. Waelter et al. (2001) identified 3 HIP1-associated proteins, clathrin heavy chain (CLTC) and alpha-adaptin A and C. Coat proteins of approximately 100-kD (adaptins) are components of the adaptor complexes which link clathrin to receptors in coated vesicles. The alpha-adaptins separate into two bands on SDS gels.

Product Specifications

Product Name Alternative

Adaptor protein complex AP-2, alpha 1 subunit (Predicted) ; Protein Ap2a1 ; Ap2a1 ; Ap2a1_predicted ; rCG_54084

Gene Name

Ap2a1

Gene ID

308578

UniProt

D3ZUY8

Host

Mouse

Reactivity

Human

Immunogen

AP-2 adaptor polypeptides from bovine brain.

Target Antigen

AP-2 complex subunit alpha-1

Clonality

Monoclonal

Clone

100/2

Applications

Purification

Ascites

Components

Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative. Reconstitute : Add 1ml of PBS buffer will yield a concentration of 100ug/mL.

Storage Conditions

At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.