Anti-S-100 (beta-subunit) Monoclonal Antibody (Clone: SH-B1)

S100 protein is a 21,000-Da component first isolated from brain by Moore (1965) . Immunocytochemical studies demonstrated that S100 protein is produced by a wide variety of normal and neoplastic cells of mesodermal, neuroectodermal, and epithelial origin (Herrera et al., 1988) . The S100 molecule is a dimer; thus there are 3 forms of S100: alpha-alpha, known as S-100a (0) ; alpha-beta, known as S-100a; and beta-beta, known as S-100b. S100 genes are clustered on human chromosome 1q21. S-100 protein expression by primary and metastatic adenocarcinomas.

Product Specifications

Product Name Alternative

Protein S100-B; S-100 protein beta chain; S-100 protein subunit beta; S100 calcium-binding protein B; S100b

Gene Name

S100b

Gene ID

25742

UniProt

P04631

Host

Mouse

Reactivity

Human

Immunogen

Bovine brain S-100b.

Target Antigen

Protein S100-B

Clonality

Monoclonal

Clone

SH-B1

Applications

IHC-P

Purification

Ascites

Components

Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative. Reconstitute : Add 1ml of PBS buffer will yield a concentration of 100ug/mL.

Storage Conditions

At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.