Monoclonal Antibody to Anti-HSP60 Antibody (Clone: LK1)

Heat shock 60KD protein (HSP60) is a member of the chaperonin class of protein factors and the nuclear encoded mitochondrial HSP60 is required for the assembly into oligomeric complexes of proteins imported into the mitochondrial matrix. HSP60 is linked head to head comprising approximately 17 kb and consist of 12 exons. HSP60 is a self-molecule, it can downregulate adaptive immune responses by upregulating Tregs innately through TLR2 signaling.

Product Specifications

Product Name Alternative

60 kDa heat shock protein, mitochondrial; 60 kDa chaperonin; Chaperonin 60; CPN60; HSP-65; Heat shock protein 60; HSP-60; Hsp60; Mitochondrial matrix protein P1; Hspd1; Hsp60

Gene Name

Hspd1

Gene ID

63868

UniProt

P63039

Host

Mouse

Reactivity

Human

Immunogen

Recombinant human heat shock protein 60 (HSP60)

Target Antigen

60 kDa heat shock protein, mitochondrial

Clonality

Monoclonal

Clone

LK1

Applications

WB, IHC-P

Purification

Ascites

Components

Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative. Reconstitute : Add 1ml of PBS buffer will yield a concentration of 100ug/mL.

Storage Conditions

At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.