Anti-Gelsolin Monoclonal Antibody (Clone: GS-2C4)

Gelsolin, a protein of leukocytes, platelets, and other cells, severs actin filaments in the presence of submicromolar calcium, thereby solating cytoplasmic actin gels. A gelsolin variant with 23 more N-terminal amino acids is a plasma component probably involved in the clearance of actin, the most abundant human protein, from the circulation. Gelsolin is located in 9q34. Plasma and cytoplasmic gelsolins are encoded by a single gene and contain a duplicated actin-binding domain.

Product Specifications

Product Name Alternative

Gelsolin; Actin-depolymerizing factor; ADF; Brevin; Gsn

Gene Name

Gsn

Gene ID

296654

UniProt

Q68FP1

Host

Mouse

Reactivity

Human

Immunogen

Human plasma gelsolin.

Target Antigen

Gelsolin

Clonality

Monoclonal

Clone

GS-2C4

Applications

WB, IHC-P, IHC-F

Purification

Ascites

Components

Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative. Reconstitute : Add 1ml of PBS buffer will yield a concentration of 100ug/mL.

Storage Conditions

At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.