Anti-VEGFR2 Monoclonal Antibody (Clone: KDR-1)

VEGF, a homodimeric glycoprotein of relative molecular mass 45,000, is the only mitogen that specifically acts on endothelial cells. The importance of VEGF and its receptor system in tumor growth and intervention in this system may provide promising approaches to cancer therapy. VEGF receptor 2 is a member of a receptor tyrosine kinase family. Like other growth factor receptors, upon ligand binding VEGF receptor 2 dimerises and is autophosphorylated on multiple tyrosine residues.

Product Specifications

Product Name Alternative

Vascular endothelial growth factor receptor 2; VEGFR-2; 2.7.10.1; Fetal liver kinase 1; FLK-1; Protein-tyrosine kinase receptor flk-1; CD309; Kdr; Flk1

Gene Name

Kdr

Gene ID

25589

UniProt

O08775

Host

Mouse

Reactivity

Human

Immunogen

Recombinant human extracellular domain of VEGFR-2 (KDR) .

Target Antigen

Vascular endothelial growth factor receptor 2

Clonality

Monoclonal

Clone

KDR-1

Applications

IHC-F

Purification

Ascites

Components

Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative. Reconstitute : Add 1ml of PBS buffer will yield a concentration of 100ug/mL.

Storage Conditions

At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.