Anti-Cdk7/CAK Monoclonal Antibody (Clone: MO-1.1)
CDK-activating kinases (CAKs) are multisubunit proteins that phosphorylate and thus activate certain cyclin-dependent protein kinases in the regulation of cell cycle progression. Cyclin dependent kinase7 (CDK7) gene is mapped to chromosome 2p15-cen. CDK7 functions in both cyclin binding and T-loop phosphorylation and that these 2 steps of CDK1 activation are mutually dependent.
Product Specifications
Product Name Alternative
Cyclin-dependent kinase 7; 2.7.11.22; 2.7.11.23; 39 protein kinase; P39 Mo15; CDK-activating kinase 1; Cell division protein kinase 7; TFIIH basal transcription factor complex kinase subunit; Cdk7; Cak, Cak1
Gene Name
CDK7
Gene ID
1022
UniProt
P50613
Host
Mouse
Reactivity
Human
Immunogen
Recombinant human Cdk7 protein.
Target Antigen
Cyclin-dependent kinase 7
Clonality
Monoclonal
Clone
MO-1.1
Applications
WB, IHC-F, ICC
Purification
Ascites
Components
Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative. Reconstitute : Add 1ml of PBS buffer will yield a concentration of 100ug/mL.
Storage Conditions
At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
Applications Notes
Western blot : 0.25μg/ml; Immunohistochemistry (Frozen Section) : 0.5μg/ml; Immunocytochemistry : 1μg/ml
Isotype
Mouse IgG2b
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