Anti-Cdk7/CAK Monoclonal Antibody (Clone: MO-1.1)

CDK-activating kinases (CAKs) are multisubunit proteins that phosphorylate and thus activate certain cyclin-dependent protein kinases in the regulation of cell cycle progression. Cyclin dependent kinase7 (CDK7) gene is mapped to chromosome 2p15-cen. CDK7 functions in both cyclin binding and T-loop phosphorylation and that these 2 steps of CDK1 activation are mutually dependent.

Product Specifications

Product Name Alternative

Cyclin-dependent kinase 7; 2.7.11.22; 2.7.11.23; 39 protein kinase; P39 Mo15; CDK-activating kinase 1; Cell division protein kinase 7; TFIIH basal transcription factor complex kinase subunit; Cdk7; Cak, Cak1

Gene Name

CDK7

Gene ID

1022

UniProt

P50613

Host

Mouse

Reactivity

Human

Immunogen

Recombinant human Cdk7 protein.

Target Antigen

Cyclin-dependent kinase 7

Clonality

Monoclonal

Clone

MO-1.1

Applications

WB, IHC-F, ICC

Purification

Ascites

Components

Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative. Reconstitute : Add 1ml of PBS buffer will yield a concentration of 100ug/mL.

Storage Conditions

At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.