Anti-CDK4 Monoclonal Antibody (Clone: DCS-31)

Cyclin-dependent kinase-4 (CDK4) is a protein-serine kinase involved in the cell cycle. Human cell division is regulated primarily at the G1-to-S or the G2-to-M boundaries within the cell cycle. The complexes formed by CDK4 and the D-type cyclins are involved in the control of cell proliferation during the G1 phase. CDK4 is inhibited by p16, also known as cyclin-dependent kinase inhibitor-2. CDK4 is mapped to 12q14. CDK4 expression and activity are required for cytokine responsiveness in T cells.

Product Specifications

Product Name Alternative

Cell division protein kinase 4, PSK-J3

Gene Name

CDK4

Gene ID

1019

UniProt

P11802

Host

Mouse

Reactivity

Human

Immunogen

Recombinant human Cdk4 protein.

Target Antigen

Cyclin-dependent kinase 4

Clonality

Monoclonal

Clone

DCS-31

Applications

WB, ICC

Purification

Ascites

Components

Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative. Reconstitute : Add 1ml of PBS buffer will yield a concentration of 100ug/mL.

Storage Conditions

At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.