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Anti-Calponin Monoclonal Antibody (Clone: CP-93)

Calponin is a basic 34-kD protein first isolated from chicken gizzard and bovine aorta. It is specifically expressed in smooth muscle and binds calmodulin, actin, and tropomyosin. It is able to inhibit the ATPase activity of myosin and is though to play a role in smooth muscle contraction. Calponin is a smooth muscle specific, actin-, tropomyosin- and calmodulin-binding protein thought to be involved in some way in the regulation or modulation of contraction.

Product Specifications

Product Name Alternative

Calponin-2; Calponin H2, smooth muscle; Neutral calponin; Cnn2

Gene Name

Cnn2

Gene ID

12798

UniProt

Q08093

Host

Mouse

Reactivity

Human

Immunogen

Turkey gizzard calponin

Target Antigen

Calponin-2

Clonality

Monoclonal

Clone

CP-93

Applications

WB, IHC-P, ICC

Purification

Ascites

Components

Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative. Reconstitute : Add 1ml of PBS buffer will yield a concentration of 100ug/mL.

Storage Conditions

At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

Applications Notes

Western blot : 0.25-0.5μg/ml; Immunohistochemistry (Paraffin-embedded Section) : 0.5-1μg/ml; Immunocytochemistry : 1μg/ml

Isotype

Mouse IgG1

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