Monoclonal Antibody to Melanoma Marker (MART-1 + gp100 + Tyrosinase) (A103 + HMB45 + T311)
Selected Variant
36-11073-100
Size: 100 µg
This antibody cocktail recognizes three melanoma-specific proteins, which include MART-1, Tyrosinase and gp100. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. The function of gp100 is not known but it is reported to be a useful marker for melanocytes and melanomas. This cocktail of three markers is designed for extremely sensitive labeling of formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.
Product Specifications
Product Name Alternative
MLANA||MART1
Gene Name
MLANA
Gene ID
2315
UniProt
Q16655
Host
Mouse
Reactivity
Human
Immunogen
Recombinant hMART-1 protein (A103) ; Recombinant tyrosinase protein (T311) ; Extract of pigmented melanoma metastases from lymph nodes (HMB45)
Target Antigen
Melanoma Marker (MART-1 + gp100 + Tyrosinase)
Clonality
Monoclonal
Clone
A103 + HMB45 + T311
Applications
WB, IHC
Purification
Affinity Chromatography
Format
Purified
Components
100 μg in 500 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions
Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Isotype
Mouse IgG1, kappa + Mouse IgG2a, kappa + Mouse IgG1, kappa
Price
Frequently Asked Questions
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