Monoclonal Antibody to IPO-38 (Proliferation Marker) (Clone : SPM260)
Recognizes a protein of 14-16kDa, which is a novel nuclear antigen of proliferating cells. IPO-38 antigen is present in the nuclei of proliferating cells such as Hodgkin s disease and non-Hodgkin s lymphomas, different forms of leukemias, breast and colorectal carcinomas, and PHA-stimulated lymphocytes. It is not expressed in the cells of non-stimulated lymphocytes and granulocytes. IPO-38 can be a useful marker of cell proliferation during monitoring of tumor progression.
Product Specifications
Host
Mouse
Reactivity
Human, Mouse, Rat
Immunogen
Spleen cells of a patient with hairy cell leukemia
Target Antigen
IPO-38 (Proliferation Marker)
Clonality
Monoclonal
Clone
SPM260
Applications
FACS, IF, IHC
Purification
Affinity Chromatography
Format
Purified
Components
100 μg in 500 μl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Storage Conditions
Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
Applications Notes
Isotype
Mouse IgM, kappa
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